Proposal “MedicinalGenomics_II“ (Active)Back

Title:Make DASH a Household Name In Three Different $20 Billion Industries
Owner:KevinMcKernan
Monthly amount: 30 DASH (11748 USD)
Completed payments: no payments occurred yet (5 month remaining)
Payment start/end: 2018-05-18 / 2018-10-14 (added on 2018-05-09)
Final voting deadline: in 10 days
Votes: 264 Yes / 60 No / 7 Abstain
Will be funded: No. This proposal needs additional 272 Yes votes to become funded.
Manually vote on this proposal (DashCore - Tools - Debugconsole):
gobject vote-many 9c96d18bc1a0ac3484d88bc8d84e9d86f89551217456290ccea82544d8003a4a funding yes

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Proposal description

Make DASH a Household Name In Three Different $20 Billion Industries

We propose to run a scientific project promoting medical freedom that will shock 3 large and rapidly growing industries using the DASH blockchain. This project will leave DASH with a unique and charitable reputation in three fast growing and data intensive markets. This will test the DASH blockchain as a platform that could see a tripling of its transaction volume if others see the value in this approach.

•    Make history in the Cannabis industry
•    Make history in the Scientific Publishing market
•    Make history in the Genomics industry

$71K (160 DASH): 30 DASH/month. 5 Months

*This is an expansion of a very popular and successful proposal (1058:105 Yes:No)
https://www.dashcentral.org/p/MedicinalGenomics

How?

Sequence a controversial Cannabis genome and publish it using a novel crypto-incentivized, crypto-recorded peer review process that will cut out the $25B Scientific publishing market.

Sequence the genome with the latest Next Generation Sequencing tools to encourage this 20% compound annual growth rate (CAGR) market to take notice of crypto-sponsored and crypto-published genomics.

 Publish the genome of a cannabis plant that is the center point of overly broad and controversial cannabis patents to assist in challenging these detrimental IP land grabs on medicinal plants. Publish this on the DASH Blockchain to set a new standard for a $25B/year peer review platform.

If the idea of crypto-incentivized, crypto-recorded peer review catches on, DASH could see a tripling of its transaction volume. The scientific publishing market is a $25B market. There are 2.5M scientific publications every year costing an average of $3k per submission in publication costs and the submission frequency is doubling every 9 years. This $7.5B review market is prime for cutting out the expensive middleman as it is cracking at the seams under ancient Gutenberg incentive models. The internet has made the cost of publication near zero and DASH has already solved the censorship resistance problem, consensus, trust and permanence problems as well. The journals are no longer needed and the market is sprung to remove their parasitic copyright enabled grasp on scientific data and truth dissemination.
                 https://www.medicinalgenomics.com/wp-content/uploads/2018/05/peer_review_cartel.png
Today, reviewers are usually anonymous and free. They have the accuracy of a twitter troll. Journals copyright the scientific work themselves and charge the researchers or the public to access it later, even if the work is publically funded. Half of the papers published can’t be reproduced and the most prestigious journals have the highest retraction rates. The incentives are broken. Why pay the journals for such poor results? This is not how science should function. Researchers should be able to pay reviewers directly. Cut the copyright out and create a market for good and bad review. These reviews and manuscripts can be published on the DASH blockchain. With the addition of a price signal to the cost of Peer Review, all of the historical misalignments change. Good reviewers will build reputation and demand higher prices. Reviewers simply “rubber stamping” their friends work will be discounted with transparent non-anonymous review. Public and immutable reputation systems change the game theoretics and align incentives for accuracy.


With this simple change, new tiers of review can evolve. Platinum, gold and bronze review will speciate to afford a market where people can pay to have the work partially or fully reproduced. DASH enables this market as a financial vehicle for the reputation and payment system. It enables the notarization engine for the peer review and DASH drive uniquely delivers a distributed drive system for critical scientific data.
  
        https://www.medicinalgenomics.com/wp-content/uploads/2018/04/data_age.png
There is a strong argument for scientific data to be on a blockchain. The current scientific databasing model often reflects a tragedy of the commons where we experience a 17% annual data decay despite large government subsidies to manage these databases.  Blockchains create a monetary alignment delivering 0% decay per year.  In addition to data decay, the databases lack pricing signals and thus are very cumbersome to use as they are not designed with customer pricing signals guiding the feature releases. The process to submit data to NCBI often requires a PhD-day and the uptime of these databases are frequently threatened by budget ceiling debates. The import friction seen in these socialized databases translates into key data from manuscripts being omitted from the submission process and rusting on unreliable servers in the form of “supplemental data”. Keynesian backed databases are not a reliable store for the scientific record.  

https://www.cell.com/current-biology/fulltext/S0960-9822(13)01400-0
https://peerj.com/blog/post/115284879109/authors-can-now-directly-submit-to-peerj-from-biorxiv/
http://www.cdnsciencepub.com/blog/21st-century-science-overload.aspx

If the $7.5B peer reviewed publications get converted to Crypto-bounties and paid in DASH to 2-3 reviewers per journal article, this alone could triple the transaction volume of DASH.

2.5M publications per year = ~7,000 publications/day * 2-3 reviewers/manuscript to be bountied in DASH. This delivers an estimated $5B-$7B in velocity of DASH. This does not include the notarizations for the review process or the pre-print server market.
  
     https://www.medicinalgenomics.com/wp-content/uploads/2018/04/pre_print_server.png
The growth of the pre-print servers are now hosting 1200 new manuscripts per month and would likely require 100 notarizations per article to include the manuscript, figures, and all communications between the authors and editors. If DASH were to capture the whole market (unlikely with this proposal alone), it would entail hashing 12K-24K transactions per month.  It is important to underscore that this proposal is a proof of concept. Getting BioRXIV, F1000 and PLoS to adopt such an approach is more likely to happen if we demonstrate it can be done.

The remaining $17.5B in the scientific publishing market is advertisements and subscription fees. Once DASH has the eyeballs for the scientific content and trust delivery platform, both of these markets can be reached with DASH currency and DASH drive.

The DASH investment in alternative media to promote truth in our media is greatly augmented if we are concurrently seen as a beacon of scientific truth.

DASH already has large investments in the Cannabis industry with Alt36, Kannapedia.net and CannMed funding. Sequencing the genome of the most ominous patent issuance will make DASH a household name in the Cannabis Industry.

The genomics market is a quickly emerging personalized medicine market. It changes the medical paradigm of one-sized fits all drugs and herd medicine to one that is more individualistic. Political structures prevent cannabis genomics from being funded. This maket is very data and CPU intensive and various Genomic Blockchain companies are getting funded to use ETH (Nebula, Shivom, LunaDNA, Zenome, Encrypgen). This is the right time to get those companies thinking about the more appropriate architecture of DASH for this $20B market.

The pre-proposal project is already capturing headlines at Dash Force News, The Cannabis Connection, The Tatiana Show, and the Future Tech Podcast.
•    https://www.youtube.com/watch?v=pAGwhueEub8
•    April 27th - http://kscocom/shows/43015-the-cannabis-connection
•    https://www.futuretechpodcast.com/podcasts/kevin-mckernan-medicinal-genomics-pioneering-study-cannabis-genetics-dna-based-measurement-microbial-risks/
•    https://www.dashforcenews.com/dash-gaining-traction-in-cannabis-industry-proposal-seeks-funding-for-genome-research/

Future exposure is planned at The Broad Institute geXc conference, The society for in-vitro biology, and CannMed 2018
•    https://www.gexcsymposia.com.
•    https://sivb.org/meetings/home/scientific-program-3.html
•    https://Cannmedevents.com

TECHNICAL DETAILS
https://www.medicinalgenomics.com/wp-content/uploads/2018/05/disrupt-three-20b-industries-with-dash_5_7_2018_tech.docx

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Discussion: Should we fund this proposal?

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-1 point,8 days ago
This is very far from making Dash money and while I support using Dash for cannabis trade this project seems somewhat removed even from that. Voting no.
Reply
0 points,2 days ago
You need to review the proposal more carefully, 3d1409ae. I know it's complicated, but it's worth taking the time to understand it. If the proposal accomplishes what it sets out to do, it could drive a significant amount of traffic to the network in the future, especially when DashDrive becomes available and monetized. These are all very large industries that are currently largely sequestered in to a few particular avenues of payment, and Kevin's project is attempting to open those up with Dash as a far more attractive and pragmatic solution.

Bringing even a small percentage of those industries to Dash would be an enormous benefit in terms of ROI. The project does not ask terribly much, but potentially provides enormous economic benefit, and that's not even getting in to the philanthropic aspect of all of this. I urge you to reconsider your assessment.
Reply
0 points,8 days ago
Thank you for critique.

The proposal is indeed more focused on getting more DASH awareness and potential transaction volume in multiple different markets.

For a digital cash to succeed in the cannabis trade, we need better standards so customers can verify what is being sold.
Cannabis is hypervariable and Customer know this.

A reference genome builds the standards by which we fingerprint strains to provide biological barcodes for products in the industry.

This is analogous to forming a consensus on what the blocksize should be. Without this reference we can’t agree on what the product is and digital trade becomes compromised.

If DASH wants to become a trust worthy monetary solution in this market it needs marketing to build its name and reputation in the space. There is no better way to build credibility in the space than by constructing the reference genome of the plant and to cement DASHs name as the arbiter of scientific truth in the field.
The future of cannabis seed to sale tracking systems will be DNA fingerprint based. If this is a DASH derived reference genome, there is a higher likelihood of adoption of DASH as the monetary platform.

This white-paper may help to describe the importance of this for the field.

https://www.medicinalgenomics.com/blockchained-cannabis-dna/
Reply
1 point,9 days ago
Lots of potential for this very affordable project, easy yes!
Reply
0 points,9 days ago
A great talk about the impact this is having on people. John Gaitanis MD at CannMed 2017.
https://medicinalgenomics.wistia.com/medias/clhm384o9y
Reply
1 point,9 days ago
Thank you for the support. I will be speaking about this project at The Broad Institute of MIT & Harvard on May 18th to a sold out crowd of 300 researchers at the Genomics and Computational Genomics Symposium. https://www.gexcsymposia.com. The Broad is hands down the largest and most prolific genome center in the world. Their publication depth is impressive and they will be interested in this project.
Reply
1 point,10 days ago
voting YES. Lets see this project come to fruition. Beyond that, I agree with sentiments regarding science journals.
Reply
1 point,10 days ago
Easy yes. Any one of the three parts of this proposal would be easily worth the modest price.

solarguy
Reply
2 points,10 days ago
/support
Reply
2 points,10 days ago
LOL, I love the way you put it this time around! Well done! I can't imagine anyone who is sick and tired of big pharma and crony capitalists saying no!

Plus, protecting everyone on earth from greedy companies who want to own a natural plant, that's insane! I hope you can prove that almost none of their plant is uniquely changed from previous cannabis plants. The world has no sense anymore.

Aside from that, from Dash's point of view, being used to register REAL innovation, at minimal cost, really almost free, taking the advantage away from those who own the system, would be something Dash could be proud of!

A big yes from me!
Reply